I put about 7K miles on my 511" FE, with about 12:1 static compression, and ran it all on pump premium. I only added race gas at the track. If your intake valve closes late enough, you shouldn't have to add any race gas to the mix to run on the street.
Jay Brown
1968 Shelby GT 500 Convertible, 492" 667 HP FE
1969 R code Mach 1, 490" supercharged FE, 9.35 @ 151.20, 2007 Drag Week Runner Up, Power Adder Big Block
2005 Ford GT, 2006 Drag Week Winner, 12.0 Daily Driver
1969 Ford Galaxie XL, 460 (Ho Hum....)
1964 Ford Galaxie 500, 510" SOHC